Mannix is a PhD student in the Molecular Biology Interdepartmental Program at UCLA where he is co-mentored by Jessica Li and Steve Jacobsen. Before joining UCLA, he received his B.A. in Biology at Boston University and worked as a researcher at Harvard Medical School and the Salk Institute. His interests include developing computational methods to address unanswered biological questions and improving statistical rigor and reproducibility in the field of biology.

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Publications:

• Liao J, Ho J, Burns MJ, Dykhuizen EC, Hargreaves, DC (2024). Collaboration between distinct SWI/SNF chromatin remodeling complexes directs enhancer selection and activation of macrophage inflammatory genes. Immunity
• Maxwell MB, Hom-Tedla MS, Yi J, Li S, Rivera SA, Yu J, Burns MJ, McRae HM, Stevenson BT, Coakley KE, Ho J, Gastelum KB, Bell JC, Jones AC, Eskander RN, Dykhuizen EC, Shadel GS, Kaech SM, Hargreaves DC (2024). ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity. Cell
• Mangalhara KC*, Varanasi SK*, Johnson MA, Burns MJ, Rojas GR, Esparza Moltó PB, Sainz AG, Tadepalle N, Abbott KL, Mendiratta G, Chen D, Farsakoglu Y, Kunchok T, Hoffmann FA, Parisi B, Rincon M, Vander Heiden MG, Bosenberg M, Hargreaves DC, Kaech SM, Shadel GS (2023). Manipulating mitochondrial electron flow enhances tumor immunogenicity. Science
• McDonald B*, Chick BY*, Ahmed NS, Burns MJ, Ma S, Casillas E, Chen D, Mann TH, O’Connor C, Hah N, Hargreaves DC, Kaech SM (2023). Canonical BAF complex activity shapes the enhancer landscape that licenses CD8+ T cell effector and memory fates. Immunity
• Lim ET, Chan Y, Dawes P, Guo X, Erdin S, Tai DJC, Liu S, Reichert JM, Burns MJ, Chan YK, Chiang JJ, Meyer K, Zhang X, Walsh CA, Yankner BA, Raychaudhuri S, Hirschhorn JN, Gusella JF, Talkowski ME, Church GM (2022). Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder. Nature Communications
• Ahmed N, Gatchalian J, Ho J, Burns MJ, Hah N, Wei Z, Downes M, Evans RM, Hargreaves DC (2022). Bromodomain protein 9 (BRD9) regulates interferon-stimulated genes during macrophage activation via cooperation with BET protein BRD4. PNAS
• Burns M, Epstein B, Burghardt L (2021). Comparison of Nodule Endophyte Composition, Diversity, and Gene Content between Medicago truncatula Genotypes. Phytobiomes Journal
• Burns M, Rizvi SHM, Tsukahara Y, Pimentel DR, Luptak I, Hamburg NM, Matsui R, Bachschmid MM (2020). Role of Glutaredoxin-1 and Glutathionylation in Cardiovascular Diseases. Int J Mol Sci.